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Synthesis of unnatural amino acids and other blocks

[Phe2,Orn8]-Oxytocin

Name
[Phe2,Orn8]-Oxytocin
Molecular structural formula
Purity
≥95%
CAS Number
2480-41-3
Formula
C42H65N13O11S2
MW
992.19
Target
others
Sequence
Cys-Phe-Ile-Gln-Asn-Cys-Pro-Orn-Gly- NH2 (Disulfide bridge:Cys1-Cys6)
Sequence Shortening
CFIQNCP-{Orn}-G-NH2 (Disulfide bridge: Cys1-Cys6)
InChIKey
BSYJBXQZRHPHRD-OVCMMVBBSA-N
References
[1]. Sandra Filippi, et al. Estrogens, But Not Androgens, Regulate Expression and Functional Activity of Oxytocin Receptor in Rabbit Epididymis. Endocrinology. 2002, 4271-4280.
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(Phe2,Orn8)-Oxytocin is a selective V1 vasopressin agonist. (Phe2,Orn8)-Oxytocin induces a sustained contractility of rabbit epididymis with EC50 value of 280 nM.